Discussion and summary

Summary, Discussion and Perspectives

Summary and General Discussion

The research described in this thesis was aimed at improving velocity measurements of blood flow in the ventricles using cardiac Magnetic Resonance Imaging. The incentive for this work was the clinical need to quantify the severity of mitral valve regurgitation in an absolute sense. MRI is an important non-invasive diagnostic tool in cardiology. Besides imaging the anatomy, the MR phase contras...

Summary and general discussion

6 241 Summary and general discussion 6

suMMary and dIscussIon

Summary and General Discussion

and discussion of results Increased plasma levels of LDL cholesterol, total cholesterol, TG, apoB and apoE, as well as decreased plasma levels of HDL cholesterol, apoA1 and apoA2 are intermediate phenotypes of CVD. These quantitative traits in the lipid metabolism pathway are considered to be among the main risk factor for development of atherosclerosis 1,2 , the primary cause of CVD. Over the ...